Hi CT, I’m not quite sure what you mean but I would begin by establishing why the weight to be carried has changed by 10Ibs+. Has the horse’s OH Rating fallen by the same or similar amount or is the horse running in a higher (relatively speaking) class of race. I’m sure one of the VDW guru’s can help.
I know last year in Raceform’s Stable Talk the trainer of Pilca stating the intention of running the horse off a low weight in higher classed handicaps as the horse wasn’t the same when carry a large amount of lead and the plan certainly worked. Good luck anyway mate.